Mix chili powder, cumin, oregano, paprika, onion powder, and garlic powder in a small bowl and set aside.

Heat oil in a large skillet over medium heat. Add chopped onion and cook until lightly browned, about 5 minutes.

Add ground beef and break it apart while cooking. Sprinkle seasoning mixture and salt and pepper over the meat. Cook until fully browned. Stir in minced garlic and cook 1 minute.

Pour in tomato sauce and stir well. Simmer uncovered for 25 minutes. Stir in chopped parsley after simmering.

Cook macaroni according to package directions until al dente. Drain without rinsing and add to beef mixture. Stir well to combine.

For broiled cheese topping: Preheat broiler. Sprinkle cheese over beefaroni and broil until melted and lightly browned.

For baked casserole: Preheat oven to 350 F. Transfer beefaroni to a greased casserole dish, top with cheese, and bake 20 to 30 minutes until melted.